Botox could ease arthritis and cancer without side effects: Single injection could offer pain relief for months

Botox, best known for smoothing out wrinkles, could also help soothe the pain of cancer, arthritis and migraines – without any side effects.
Sufferers of chronic back pain and women who have given birth by Caesarean section could also benefit from the ‘super-Botox’ jab.
A single injection could provide pain relief for months – removing the need for patients to take several daily doses of powerful tablets – and it could be injected into any part of the body.
Charities said the drug, invented by a researcher at Sheffield University, could revolutionise the treatment of pain.
The main ingredient of the Botox used to prevent wrinkles is a bacterial poison known as botulinum.
It works by preventing nerve cells from talking to muscles, which in turn stops muscles moving and wrinkles developing.
It can also stop pain signals from being transmitted for months at a time. The tetanus toxin ferries the pain-reliever to the spinal cord, where it stops pain signals being sent to the brain.
This News is brought to you courtesy of Dr. Mark Bishara and The Paragon Plastic Surgery & Med Spa in Mansfield and Southlake, TX

Botox gives chronic migraine relief

Lady receiving Botox injectable treatment to the forehead 
Statistics show that 70,000 people in Scotland regularly suffer chronic migraines. For Gillian Patterson, Botox has provided her with much-needed relief.
Since being a university student, Gillian has suffered from excruciating migraines which meant she was forced to lay in bed for two or three days with the curtains closed, the lights off, paralysed by pain. The migraines also meant she was unable to hold a conversation or even think.
Speaking about those experiences, Gillian says: “Lots of things go through your head at times like that, such as ‘I’ve had enough. I can’t take any more.’ But most of the time it was like a mental paralysis.”
Gillian, now 40 from Jordanhill in Glasgow was first diagnosed when she was 20, forcing her to give up her hopes of graduating in French and business computing.
Her first migraine struck after a kidney transplant operation. The World Health Organisation lists migraines as one of the world’s 20 most disabling conditions.
Gillian has now been given fresh hope from Botox. Usually associated with anti ageing- the treatment is now being offered as a cure to migraines. Tests showed that patients who suffered from 19.1 days of migraines a month, suffered 8.2 less following Botox treatment.
Gillians first treatment included 33 injections to the head, neck and shoulders, paralysing the muscles so pain signals can’t pass to the brain.
Since then, the amount of drugs she needs to control the migraines has been halved and has now undergone her second treatment. Gillian is safe to have three treatments per year.
This News is Brought to You Courtesy of Dr. Mark Bishara and The Paragon Plastic Surgery & Med Spa in Mansfield and Southlake, TX

The history of BOTOX®

BOTOX® (onabotulinumtoxinA) is a type of medicine that is used to treat patients with certain neuromuscular conditions. One of the most researched medicines in the world, BOTOX® treatment is approved for medical uses across the world.

Since its FDA approval for aesthetic treatment in April 2002, the neurotoxin Botox has gone from a somewhat controversial treatment to a celebrity-endorsed wrinkle remedy. Injectables have become the new norm in cosmetic treatment. According to the American Academy of Facial Plastic and Reconstructive Surgery, the most common nonsurgical procedures last year were Botox and hyaluronic acid fillers.
It’s come a long way from its origins as an FDA approved treatment for two rare eye muscle disorders (strabismus and blepharospasm). The original name, Oculinum, doesn’t exactly roll off the tongue, but shortly after Allergan secured that first FDA approval in 1989, the product was rebranded Botox. Once physicians realized that Botox could treat wrinkles, the rest was history.
Botox reached nearly $1.6 billion in sales last year, attributing 51 percent to therapeutic uses and 49 percent to aesthetic uses. It became so successful that it gained its first FDA-approved wrinkle-reducing competitor in 2009-the sincerest form of flattery in the business world. However, Botox continues to evolve as new uses for the product are discovered. Used off-label, it treats a host of concerns such as crow’s-feet, down-turned corners of the mouth and bands on the neck. You may be surprised to learn that it has also been used, off label, to aesthetically treat enlarged pores, droopy eyebrows, a pointy chin and a droopy nose tip. Additionally, it’s an FDA-approved treatment for medical conditions ranging from chronic migraine to excessive sweating. Next up: the company is seeking FDA approval for the treatment of crow’s-feet.

1950s- Scientists discover that botulinum toxin can reduce muscle spasms.
1960s/1970s- Studies explore botulinum toxin as a treatment for strabismus (crossed eyes).
1988- Allergan researches other medical uses of botulinum toxin.
1989- Allergan introduces BOTOX®, the first botulinum toxin approved by the FDA to treat blepharospasm (eyelid spasms) and strabismus.
2000- FDA approves BOTOX® therapy for cervical dystonia to reduce the severity of abnormal head position and neck pain.
2002- FDA approves BOTOX® Cosmetic (onabotulinumtoxinA), the same formulation as BOTOX®, with dosing specific to moderate to severe frown lines between the brow.
2004- FDA approves BOTOX® for severe underarm sweating when topical medicines don’t work well enough.
2009- 20-year anniversary of BOTOX®
2010- FDA approves BOTOX® therapy for increased muscle stiffness in elbow, wrist, and finger muscles with upper limb spasticity.

2011- FDA approves Botox for detrusor overactivity associated with neurologic condition
2013- FDA approves to improve symptoms of overactive bladder in adults
BOTOX® is the first medicine to be studied and then approved by the FDA specifically for the prevention of headaches in adults with Chronic Migraine who have 15 or more days each month with headache lasting 4 or more hours each day in people 18 years or older.
Compared to other cosmetic procedures, BOTOX® offers patients many benefits with its convenience, effectiveness and affordability. The entire procedure takes about ten minutes to perform, and patients can go home and return to regular activities immediately after. The results of BOTOX® injections are visible within the next few days.
At Dr. Bishara’s office we have weekly Botox specials in our Mansfield and Southlake office locations.  Please call our office at (817) 473-2120 to find out more about our weekly Botox specials or visit our website at